Marcel Dinger, Ph.D.
Head, Kinghorn Centre for Clinical Genomics
Laboratory Head, Genome Informatics
Garvan Institute of Medical Research
Conjoint Associate Professor,
St Vincent’s Clinical School, Faculty of Medicine, UNSW Australia
Long noncoding RNAs (lncRNAs) are increasingly recognized as having key regulatory roles in development and disease. However, these regulatory molecules often have short half lives and are expressed only in specific tissues or cell types, resulting in the poor representation of lncRNAs in transcriptomic datasets. Using novel detection and sampling approaches, we reveal a high-resolution spatiotemportal view of the long noncoding transcriptome that provides fresh insights into their roles in development and disease.
Hosted by Olivier Elemento, Ph.D.