Positions Available

Postdoctoral position in computational biology

A postdoctoral position in computational biology is available in the lab of Doron Betel at Weill Cornell Medical College in New York City. Our work is focused on the development and application of computational tools for the study of post-transcriptional regulation specifically miRNA and other small regulatory RNAs. We have several active collaborations with experimentalist and clinicians at Weill Cornell as well as other institutes in the areas of cancer, stem cell and neurobiology. Postdocs in the group will have the opportunity to take a leadership role in one or more of these projects, initiate new projects and foster new collaborations. We currently have a position open to work on the analysis and interpretation of miRNA targets and RNA expression data in cancer and neurobiology using novel experimental and high-throughput sequencing approaches.

An ideal candidate should have Ph.D (or equivalent) training in statistics, machine learning, algorithmic development and computational biology as well as detail understanding of molecular biology and genetics. Prior experience in processing and managing high-throughput sequencing data is desired.

Applications will be accepted until the position is filled. Please submit a CV, a brief research statement, bibliography (or preprints), and names of at least three references to Doron Betel (dob2014@med.cornell.edu).

Postdoctoral Research Positions in Molecular Modeling

Applications are invited for postdoctoral research positions at any level (from junior to senior) to study the structure-function-dynamic relations of proteins at Weill Cornell Medical College. The ideal candidate to fill this position should have a Ph.D. in molecular biophysics, computational chemistry, or bioinformatics and have solid knowledge background and experience with protein structure, modeling and simulations. Compensation commensurate with experience. To apply please send materials including CV to Lei Shi, Ph.D., Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College, 1300 York Avenue Box 75, Room LC501E, New York, NY 10065 (les2007@med.cornell.edu).

Postdoctoral Research Positions in Cancer Genomics

Description: A Starr Cancer Consortium Foundation-funded post-doctoral position in cancer genomics is available in the Institute for Computational Biology at Weill Cornell Medical College of Cornell University. The position is focused on untangling large scale data emerging from DNA genome and RNA transcriptome sequencing in the area of prostate cancer. The ability to understand the functional implications of mutations and deregulation of genes and pathways will provide novel insight into the disease process and help nominate putative therapeutic targets.

The postdoc will work under the direct supervision of Francesca Demichelis (Leader of the Computational Group for Prostate Cancer at Weill Cornell). Key interactions will occur with collaborators in the Department of Pathology and Laboratory Medicine (Mark A. Rubin, Prostate Cancer Pathology Laboratory) and the Broad Institute (Levi Garraway, Prostate Cancer Functional Group) to 1) identify, characterize, and prioritize .driver. genomic mutations (e.g., in/dels, non-synonymous mutations, gene fusions events, etc.), 2) Determine canonical pathways that are altered due to a combination of mutations and deregulation of transcriptomic events to help determine key functional targets, 3) Develop novel approaches to integrate DNA-sequencing, RNA-Sequencing, and somatic copy number alteration data with the goal of providing novel insights no currently available from existing computational approaches.

Qualifications: A strong computational background and basic knowledge of statistics are required. Specific knowledge of Cancer Biology is not required but would be an asset. The ideal candidate will need to interact well with non-computational biologist in a systems biology approach. A Ph.D. in either computational biology or genomics, or in a closely-related field, is required by the position start-date.

Contact Information: Interested candidates should send a curriculum vitae and brief summary of research experience to: Francesca Demichelis, Ph.D.; Department of Pathology and Laboratory Medicine, Institute for Computational Biomedicine, Weill Cornell Medical Center, 1305 York Avenue, Room Y-1307, Box 140; New York, NY 10021. Email: frd2004@med.cornell.edu

Post-doctoral Position in Functional and Computational Genomics

A full-time postdoctoral position is immediately available in Christopher Mason's lab at the Weill Medical College of Cornell University and Institute for Computational Biomedicine in New York City.

The Mason lab focuses on the development of new algorithms for the analysis of next-generation sequence (NGS) data, including the creation of the BioHDF (Hierarchical Data Format) structures. We also work on the parallelization of automated analytic steps and visualization of enormous data sets (trillions of data points). In this lab, you would develop novel programs for DNA and RNA variant detection from RNA-Seq and other NGS data, with multi-dimensional integration of these data along regulatory and developmental layers, including new methods in immersive environments and gesture-based computing. You would help classify genetic variants that are found leukemia and lung disease patients, validate them, and then utilize these methods to examine other datasets from our lab, such as normal brain samples studied as part of neurogenetics time course and Autism samples.

Excellent bioinformatic and programming skills (e.g., in C, C++, Perl, Python, or Java), a strong background in genetics and biology, and expertise in statistics are necessary for this position. Prior experience with analysis of deep sequencing, expression, and CNV data would be ideal. Salary will be competitive with entry-level post-docs, but experience can obviously increase the starting salary. Benefits are excellent at Cornell.

To apply, email a resume in addition to names and contact addresses of two persons who can provide recommendation letters to:

Christoper Mason
chm2042@med.cornell.edu
http://physiology.med.cornell.edu/faculty/mason/lab/
Weill Medical College of Cornell University
Institute for Computational Biomedicine
1305 York Avenue
New York, NY, 10021

Postdoctoral Position in Computational Genomics

A full-time postdoctoral position is available in Olivier Elemento's group at the Weill Medical College of Cornell University and Institute for Computational Biomedicine in New York City.

The group's research emphasis is the systems and computational biology of regulatory networks in normal and malignant cells. As part of our research, we develop and apply innovative computational tools and modeling techniques to generate testable hypotheses and reveal fundamental principles about regulatory network connectivity, regulatory mechanisms, regulatory sequences, drug targets, and other molecular aspects of cancer cells. Experimental testing of these hypotheses and generation of new data (e.g., ChIP-seq and RNA-seq) is done in collaboration with other groups at Weill Cornell and elsewhere.

Strong programming skills (e.g., in C, C++, or Java), expertise in statistics and machine learning are necessary for this position. Prior experience with analysis of deep sequencing or proteomic data would be a plus.

To apply, email a resume in addition to names and contact addresses of two persons who can provide recommendation letters to:

Olivier Elemento
ole2001@med.cornell.edu
http://physiology.med.cornell.edu/faculty/elemento/lab/
Weill Medical College of Cornell University
Institute for Computational Biomedicine
1305 York Avenue
New York, NY, 10021

Faculty Positions and Fellowships

The field of systems biology is undergoing exciting changes. In the last decade, there have been major technological advances, both at the experimental and theoretical levels. These include the development of large scale methods for monitoring neuronal activity, large scale methods for monitoring gene expression, high throughput assays of behavior at various levels, and a host of mathematical and computational tools (statistical and dynamical systems-based) for tackling complex datasets. These advances open the door to major discoveries and conceptual breakthroughs in ways that were not previously possible.

To incorporate these changes into its research efforts, The Weill Medical College of Cornell University has embarked on a major expansion in this area. This includes the construction of new buildings, the establishment of a Junior Fellows program, and the opening of several new tenure track faculty positions.

The following are the current recruitments, as listed in Nature and Science.

Faculty Positions in Theoretical Neuroscience

The Institute for Computational Biomedicine at the Weill Medical College of Cornell University (on the Manhattan campus) invites applications for tenure-track faculty positions at the Assistant Professor level or higher. The applicant should have a broad range of achievements in theoretical approaches to systems biology, with a strong emphasis on neuroscience. He/she will be expected to build an exciting, first-rate research program, to participate in the training of graduate students and postdoctoral fellows, and to interact with a thriving, and rapidly growing, group of theorists and experimentalists, working at all levels of systems biology - molecular, cellular, multi-cellular (network), and behavioral.

Applications should include a curriculum vitae, a two-page summary of past research and future plans, and reprints of two or three key publications. The application and three letters of recommendation should be sent to:

Theoretical Neuroscience Search Committee,
c/o Terry Neal-Provenzano,
Manager of Faculty Recruitment
Weill Cornell Medical College
1300 York Avenue, Box 27
New York, NY 10065

For information about the Institute for Computational Biomedicine (ICB), see http://icb.med.cornell.edu/

For Information about neuroscience research at Weill Cornell, see http://neuroscience.med.cornell.edu/

Cornell is an Equal Opportunity/Affirmative Action Employer

Junior Fellow Positions in Theoretical Neuroscience

The Institute for Computational Biomedicine at the Weill Medical College of Cornell University (on the Manhattan campus) invites applications for Cornell Junior Fellow positions. These positions are targeted for young scientists, typically at the advanced postdoctoral level, of outstanding promise - scientists with the drive, perseverance, and history of accomplishments to suggest that they will, in the long run, make fundamental contributions to scientific understanding. Once chosen, Fellows are free to pursue whatever lines of inquiry interests them within the field being advertised. The fellowship offers the opportunity to pursue research independently and intensely, free from the burdens of a standard faculty position (teaching, grant writing, administrative responsibilities, etc.). The current positions being offered are for 2-3 years and target theoretical neuroscience; successful and productive Fellows will be considered prime candidates for tenure-track faculty positions.

Applications should include a curriculum vitae, a two-page summary of past research and future plans, and reprints of two or three key publications. The application and three letters of recommendation should be sent to:

Cornell Junior Fellow Search Committee,
c/o Terry Neal-Provenzano,
Manager of Faculty/Fellow Recruitment,
Weill Cornell Medical College
1300 York Avenue, Box 75
New York, NY 10065

For information about the Institute for Computational Biomedicine (ICB), see http://icb.med.cornell.edu/

For Information about neuroscience research at Weill Cornell, see http://neuroscience.med.cornell.edu/

Cornell is an Equal Opportunity/Affirmative Action Employer

News
March, 2012; Michelle Sahai, Ph.D., a Postdoctoral Associate in Harel Weinstein's lab, was awarded a three year Canadian Institutes of Health Research (CIHR) Fellowship for her research on Molecular Mechanisms of the Dopamine Transporter Function: The effects of drugs of abuse.
Feb, 2012; Sayan Mondal, a student in Harel Weinstein's lab, won the Student Research Achievement Award at the Biophysical Society's 2012 Annual Meeting for his poster on the interaction of GPCRs with the membrane.
Jan, 2012; Jan Dlabal, a student from the Lycée Français de New York, was selected as a semi-finalist in the 2012 Intel Science Talent Search, for work on the determination of large-scale genomic structure performed in the lab of Olivier Elemento.
Oct, 2011; Sheila Nirenberg presented a talk, "Can we speak the language of the brain?", at the TEDMED 2011 conference. A Q & A session followed.
Nov, 2011; GobyWeb binary release. The Campagne laboratory has just released a binary distribution of GobyWeb. This first public release of GobyWeb makes it possible to install the tool locally for non-commercial use. Detailled installation instructions are available on the download page.
Apr, 2011; Dr. Olivier Elemento was awarded an NSF CAREER Grant, the National Science Foundation's most prestigious award in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education and the integration of education and research.
Nov, 2010; Dr. Sheila Nirenberg's work on artificial retinas has been featured in Technology Review, Wired, Scientific American, and the New Scientist.
Jul, 2009; ChIPseeqer, a comprehensive framework for analysis of ChIP-seq data developed in the Elemento lab, is now available for download. [More]

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