Positions Available

Postdoctoral Position in Computational Biology

A postdoctoral position in computational biology is available in the lab of Doron Betel at Weill Cornell Medical College in New York City. Our work is focused on the development and application of computational tools for the study of post-transcriptional regulation specifically miRNA and other small regulatory RNAs. We have several active collaborations with experimentalist and clinicians at Weill Cornell as well as other institutes in the areas of cancer, stem cell and neurobiology. Postdocs in the group will have the opportunity to take a leadership role in one or more of these projects, initiate new projects and foster new collaborations. We currently have a position open to work on the analysis and interpretation of miRNA targets and RNA expression data in cancer and neurobiology using novel experimental and high-throughput sequencing approaches.

An ideal candidate should have Ph.D (or equivalent) training in statistics, machine learning, algorithmic development and computational biology as well as detail understanding of molecular biology and genetics. Prior experience in processing and managing high-throughput sequencing data is desired.

Applications will be accepted until the position is filled. Please submit a CV, a brief research statement, bibliography (or preprints), and names of at least three references to Doron Betel (dob2014@med.cornell.edu).

Postdoctoral Research Positions in Molecular Modeling

Applications are invited for postdoctoral research positions at any level (from junior to senior) to study the structure-function-dynamic relations of proteins at Weill Cornell Medical College. The ideal candidate to fill this position should have a Ph.D. in molecular biophysics, computational chemistry, or bioinformatics and have solid knowledge background and experience with protein structure, modeling and simulations. Compensation commensurate with experience. To apply please send materials including CV to Lei Shi, Ph.D., Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College, 1300 York Avenue Box 75, Room LC501E, New York, NY 10065 (les2007@med.cornell.edu).

Postdoctoral Research Positions in Cancer Genomics

Description: A Starr Cancer Consortium Foundation-funded post-doctoral position in cancer genomics is available in the Institute for Computational Biology at Weill Cornell Medical College of Cornell University. The position is focused on untangling large scale data emerging from DNA genome and RNA transcriptome sequencing in the area of prostate cancer. The ability to understand the functional implications of mutations and deregulation of genes and pathways will provide novel insight into the disease process and help nominate putative therapeutic targets.

The postdoc will work under the direct supervision of Francesca Demichelis (Leader of the Computational Group for Prostate Cancer at Weill Cornell). Key interactions will occur with collaborators in the Department of Pathology and Laboratory Medicine (Mark A. Rubin, Prostate Cancer Pathology Laboratory) and the Broad Institute (Levi Garraway, Prostate Cancer Functional Group) to 1) identify, characterize, and prioritize .driver. genomic mutations (e.g., in/dels, non-synonymous mutations, gene fusions events, etc.), 2) Determine canonical pathways that are altered due to a combination of mutations and deregulation of transcriptomic events to help determine key functional targets, 3) Develop novel approaches to integrate DNA-sequencing, RNA-Sequencing, and somatic copy number alteration data with the goal of providing novel insights no currently available from existing computational approaches.

Qualifications: A strong computational background and basic knowledge of statistics are required. Specific knowledge of Cancer Biology is not required but would be an asset. The ideal candidate will need to interact well with non-computational biologist in a systems biology approach. A Ph.D. in either computational biology or genomics, or in a closely-related field, is required by the position start-date.

Contact Information: Interested candidates should send a curriculum vitae and brief summary of research experience to: Francesca Demichelis, Ph.D.; Department of Pathology and Laboratory Medicine, Institute for Computational Biomedicine, Weill Cornell Medical Center, 1305 York Avenue, Room Y-1307, Box 140; New York, NY 10021. Email: frd2004@med.cornell.edu

Post-doctoral Position in Functional and Computational Genomics

A full-time postdoctoral position is immediately available in Christopher Mason's lab at the Weill Medical College of Cornell University and Institute for Computational Biomedicine in New York City.

The Mason lab focuses on the development of new algorithms for the analysis of next-generation sequence (NGS) data, including the creation of the BioHDF (Hierarchical Data Format) structures. We also work on the parallelization of automated analytic steps and visualization of enormous data sets (trillions of data points). In this lab, you would develop novel programs for DNA and RNA variant detection from RNA-Seq and other NGS data, with multi-dimensional integration of these data along regulatory and developmental layers, including new methods in immersive environments and gesture-based computing. You would help classify genetic variants that are found leukemia and lung disease patients, validate them, and then utilize these methods to examine other datasets from our lab, such as normal brain samples studied as part of neurogenetics time course and Autism samples.

Excellent bioinformatic and programming skills (e.g., in C, C++, Perl, Python, or Java), a strong background in genetics and biology, and expertise in statistics are necessary for this position. Prior experience with analysis of deep sequencing, expression, and CNV data would be ideal. Salary will be competitive with entry-level post-docs, but experience can obviously increase the starting salary. Benefits are excellent at Cornell.

To apply, email a resume in addition to names and contact addresses of two persons who can provide recommendation letters to:

Christoper Mason
chm2042@med.cornell.edu
http://physiology.med.cornell.edu/faculty/mason/lab/
Weill Medical College of Cornell University
Institute for Computational Biomedicine
1305 York Avenue
New York, NY, 10021

Postdoctoral Position in Computational Genomics

A full-time postdoctoral position is available in Olivier Elemento's group at the Weill Medical College of Cornell University and Institute for Computational Biomedicine in New York City.

The group's research emphasis is the systems and computational biology of regulatory networks in normal and malignant cells. As part of our research, we develop and apply innovative computational tools and modeling techniques to generate testable hypotheses and reveal fundamental principles about regulatory network connectivity, regulatory mechanisms, regulatory sequences, drug targets, and other molecular aspects of cancer cells. Experimental testing of these hypotheses and generation of new data (e.g., ChIP-seq and RNA-seq) is done in collaboration with other groups at Weill Cornell and elsewhere.

Strong programming skills (e.g., in C, C++, or Java), expertise in statistics and machine learning are necessary for this position. Prior experience with analysis of deep sequencing or proteomic data would be a plus.

To apply, email a resume in addition to names and contact addresses of two persons who can provide recommendation letters to:

Olivier Elemento
ole2001@med.cornell.edu
http://physiology.med.cornell.edu/faculty/elemento/lab/
Weill Medical College of Cornell University
Institute for Computational Biomedicine
1305 York Avenue
New York, NY, 10021