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Past Events › Institute for Computational Biomedicine (ICB) Seminar

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April 2015

Swarm Transmission, Adaptation, and Evolutionary Dynamics of Influenza A Virus

April 8, 2015 @ 11:00 am - 12:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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Elodie Ghedin Professor of Biology and Public Health Center for Genomics & Systems Biology Global Institute of Public Health New York University Hosted by Drs. Betel and Elemento

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Genetics of Autism Spectrum Disorders

April 22, 2015 @ 11:00 am - 12:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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Michael Wigler, Ph.D. Professor, Mammalian Cell Genetics and Interim Chair, Quantitative Biology, Cold Spring Harbor Laboratory Hosted by Drs. Betel and Elemento

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May 2015

Decoding the Genome: Dissecting the Regulatory Repertoire of the Genome through High-Resolution Transcriptomics

May 4, 2015 @ 4:00 pm - 5:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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Marcel Dinger, Ph.D. Head, Kinghorn Centre for Clinical Genomics Laboratory Head, Genome Informatics Garvan Institute of Medical Research Conjoint Associate Professor, St Vincent’s Clinical School, Faculty of Medicine, UNSW Australia   Long noncoding RNAs (lncRNAs) are increasingly recognized as having key regulatory roles in development and disease. However, these regulatory molecules often have short half lives and are expressed only in specific tissues or cell types, resulting in the poor…

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Predicting cancer-specific vulnerability via data driven detection of synthetic lethality

May 13, 2015 @ 11:00 am - 12:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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Eytan Ruppin, M.D., Ph.D. Professor Department of Computer Science Director of the Center for Bioinformatics and Computational Biology   Hosted by Drs. Doron Betel and Olivier Elemento

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Molecular classification of medulloblastoma: clinical utility and biological insight

May 14, 2015 @ 2:00 pm - 3:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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David J. H. Shih, MSc PhD Student, Cancer Genomics University of Toronto (Postdoctoral Candidate, Ekta Khurana’s Lab)   HOST: Ekta Khurana, Ph.D.

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A Platform for Developing Bioinformatics Analytics for Cloud, Cluster and Desktop Computers

May 20, 2015 @ 11:00 am - 12:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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Konstantinos (Ntino) Krampis, Ph.D. Associate Professor Dept. of Biological Sciences, Hunter College Director of Bioinformatics, Center for Translational and Basic Research City University of New York – CUNY Adjunct Assistant Professor Dept. of Physiology and Biophysics Institute for Computational Biomedicine Weill Cornell Medical College   Hosted by Drs. Doron Betel and Olivier Elemento

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June 2015

Chalkboard to Bedside: Translating Insights from Multiscale Evolutionary Mathematical Models to the Clinic

June 3, 2015 @ 11:00 am - 12:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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Jacob Scott, M.D. Department of Radiation Oncology and Integrative Mathematical Oncology H. Lee Moffitt Cancer Center and Oxford University Centre for Mathematical Biology   Hosted by Harel Weinstein, D.Sc.

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Regulatory Variation from RNA to Protein in Humans and Primates

June 8, 2015 @ 2:00 pm - 3:00 pm
ICB Conference Room (Y13.01),
1300 York Ave, New York, NY 10021 United States
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Zia Khan, Ph.D. Assistant Professor University of Maryland, College Park Center for Bioinformatics and Computational Biology (CBCB)   Understanding how genetic differences affect phenotypic variation within and between species is a central goal of evolutionary and medical genetics. In this talk, I present two stories related to this important goal. The first is a study of mRNA expression and protein abundance divergence between human, chimpanzee, and rhesus macaque lymphoblastoid cell…

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Computational Systems Biology Approaches to Investigate Mechanisms of Progression and Therapeutic Response in Human Cancer

June 11, 2015 @ 4:00 pm - 5:00 pm
Physiology Conference Room (LC-504),
1300 York Ave, New York, NY 10065 United States
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Antonina Mitrofanova, Ph.D. Associate Research Scientist Irving Cancer Research Center Columbia University   Hosted by Olivier Elemento, Ph.D.

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July 2015

CAPRI: Efficient Inference of Selective Advantage Relationships in Cancer Progression

July 9, 2015 @ 2:00 pm - 3:00 pm
ICB Conference Room (Y13.01),
1300 York Ave, New York, NY 10021 United States
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Marco Antoniotti, Ph.D. Associate Professor Dipartimento Informatica Sistemistica e Comunicazione Universit√† Milano Bicocca   Joint work with: Daniele Ramazzotti, Giulio Caravagna, Loes Olde Loohuis, Ilya Korsunsky, Giancarlo Mauri, Bud Mishra   Abstract: Cancer is a disease of evolution whose process is characterized by the accumulation of somatic alterations to the genome, which selectively make a cancer cell fitter to survive. The understanding of progression models for cancer, i.e., the identification…

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