Courses home > Introduction to bioinformatics

The advent of high-throughput sequencing, microarray technology, genomics and proteomics has generated a wealth of data. Bioinformatics is a rapidly growing recently developed field which gives us the opportunity to gain new insights into the biology of organisms by the analysis of this huge amount of data. It combines the fields of computer science, mathematics and biology, and involves the study of the methods and problems associated with the task of bringing information to a researcher, sorting this mass of information in a meaningful way and then analyzing it. It involves the construction of bioinformatics pipelines which may include many different programs written for a specific purpose, and which can then be used by the researcher to answer diverse questions which arise in their fields.

Bioinformatics addresses:

biological data storage and retrieval

ab initio and knowledge-based prediction methods

biological data mining and analysis

visualization of biological data and information

This course will give an introduction to some of the more commonly used and more useful bioinformatics tools available on the web.

Further questions can be addressed to Lucy Skrabanek


[ tutorials ]

Bioinformatics
Sequence retrieval
Homology searching
Sequence alignment
Phylogenetic analysis
Promoter analysis


[ additional information ]

Databases of relevance to molecular biology and network sites

Letter codes for sequences

BLOSUM45 matrix

BLOSUM62 matrix

BLOSUM80 matrix

PAM30 matrix

PAM70 matrix

News
Apr, 2009; The BDVal program developed by the Campagne laboratory for MAQC-II is now available from http://bdval.org. The software supports the development and evaluation of predictive biomarker models from high-throughput data. The web site offers binary and source distributions. [More]
Jan, 2009; Twease now supports searching MEDLINE articles by Author, Journal, and Publication Year. Examples for performing these searches can be found in the updated Twease tutorial. [More]
Jan, 2009; The free bioinformatics walk-in clinics are back and will be available every Monday, 2-4pm at the Weill Cornell Medical Library, in the Computer Room on the lower level. [More]

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Events
Jul 7th; 1:00pm-2:00pm: Understanding Computation in Large Neuronal Networks - Yasser Roudi, Ph.D.; Nordic Institute for Theoretical Physics; LC-504 [Physiology and Biophysics Special Seminar]
Nov 1st: Sequencing of Individual Genomes: Impact on Society and Ethics ; Geneva, Switzerland [HUGO Symposium on Genomics and Ethics, Law and Society]