To quantitatively populate SigPath with kinetic constants and equations that may be assembled into models and automatically exported to a number of computing environments for numerical computation

To develop an initial set of guidelines on how the kinetic parameters are going to be annotated so that when a researcher uses parameters reported from another laboratory, she/he understands the validity and potential limitations in using these parameters.

[ prior to the workshop ]

To make the best use of time during the workshop, we strongly encourage participants to do some home work before the start of the workshop. We suggest that you prepare following these steps:

Define the list of signaling components for which you will enter information during the workshop.

Organize the information. Specifically, find relevant articles (keep a note of the citations), extract and/or fit constants. Define mechanisms.

Deposit a list of the components and interactions that you will work on into the electronic forum (see below). You can submit the list as a Word or Excel document, or the format of your choice. We will review the information and give you feedback before the workshop. Please deposit your documents in the forum by the 23rd of November to give other participants enough time to look at your data set before the workshop.

Start looking at documents deposited by others. If you have a question about the data in the document, we suggest that you add a note to the pathway issue, with the question. Other participants will be able to think about the question and post their thoughts. Feel free to post questions in the forum, we will use it as an elaborate post-it to collect questions/answers that we will discuss collectively at the meeting.

Mailing List - Information about the mailing list will be posted here.

Electronic forum - Use the system as a forum where you can log questions. When somebody posts an answer or a comment, you will be notified by email. Issues/Questions/Answers will be archived and searchable by keyword. (We will be creating accounts on this system for each participant.)

The forum provides examples of the kind of data that we would like participants to prepare prior to the workshop. Documents are listed under issues named after pathways (for instance "Gs pathway" and "ubiquitination pathway"). Click on an issue to see the documents and notes associated with the data set.

December 9th. 6-7 PM Welcome and introductory session.

December 10th-11th. SigPath tutorials and information submission sessions. A detailled agenda will be posted later.

December 12th. 10 AM - Noon. Wrap up session. Departure to airports.