Crover bioinformatics framework

Crover is a software framework that supports the development of Bioinformatics tools. This framework has been designed by Fabien Campagne, PhD. while at different institutions (Centre Charles Hermites, Spring 1998-September 1998; Mount Sinai School of Medicine, Department of Physiology and Biophysics, October 1998, June 2000, Mount Sinai School of Medicine, Institute for Computational Biomedicine, July 2000-).

The Crover framework is expected to be used mainly by researchers who need to automate tasks related to Bioinformatics. Crover is made of several packages that can be used together or sometimes independently. An overview of the main packages is given below.

representation
Provides for the representation of sequences and annotations. This is a most central package of crover. Other packages use the representation of sequences to perform treatments on the data.
imports
Provides for the import of sequences from files (supported formats include SwissProt, Fasta, PIR, PDB).
util
Provides a few classes which implement simple analysis tasks.
blast
Provides classes to start a BLAST process and obtain a memory representation of the results.
tissue
Supports the data management of tissue information. This package implements supporting classes and the command line tools included in TissueInfo.
domain2d
Provides implementations of algorithms to draw residue-based diagrams of proteins.
clustalnet
Provides access to clustalnet, a modified version of Clustal that offers a CORBA server.
CLI
Provides general services needed by Command Line Interface programs. These services include: configuration of the environment through a property file, methods to parse options from the command line.

A comparison of Crover with other bioinformatics framework has been presented at ISMB 2000. A reprint is now available. More information about Crover is available from our documentation area. Javadoc is used to maintain the information offered in this area from the most stable version of Crover.

For more information about this framework, or to obtain a license, please feel free to contact us.

News
Jul, 2009; ChIPseeqer, a comprehensive framework for analysis of ChIP-seq data developed in the Elemento lab, is now available for download. [More]
Apr, 2009; The BDVal program developed by the Campagne laboratory for MAQC-II is now available from http://bdval.org. The software supports the development and evaluation of predictive biomarker models from high-throughput data. The web site offers binary and source distributions. [More]
Jan, 2009; Twease now supports searching MEDLINE articles by Author, Journal, and Publication Year. Examples for performing these searches can be found in the updated Twease tutorial. [More]

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Events
Dec 11th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Fabien Campagne; ICB Conference Room - Y.1301
Jan 15th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Lei Shi; ICB Conference Room - Y.1301
Feb 12th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Christopher E. Mason; ICB Conference Room - Y.1301
Mar 12th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Olivier Elemento; ICB Conference Room - Y.1301
Apr 9th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Emre Aksay; ICB Conference Room - Y.1301
May 14th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Jonathan D. Victor; ICB Conference Room - Y.1301
Jun 11th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Harel Weinstein; ICB Conference Room - Y.1301
Jul 9th; 4:00pm-5:00pm: Institute for Computational Biomedicine Research in Progress Seminar Series - Duane Hassane; ICB Conference Room - Y.1301